Pancreatic Cancer

Pancreatic cancer originates in the tissues of the pancreas, an organ that lies behind the lower part of the stomach. It progresses through various stages and is often difficult to detect early. Initial symptoms may include jaundice, abdominal pain, weight loss, and changes in stool. In India, pancreatic cancer is increasingly common, affecting many individuals annually, predominantly those aged 50 and above, often with a family history or certain genetic predispositions.

Symptoms:

Early signs may include:

  • Jaundice (yellowing of the skin and eyes)
  • Abdominal pain that radiates to the back
  • Unexplained weight loss
  • Loss of appetite
  • Nausea and vomiting
  • Changes in stool (e.g., greasy stools)
  • New-onset diabetes or existing diabetes that becomes harder to control
  • Blood clots
  • Fatigue

Causes:

The exact cause remains unclear, but risk factors include:

  • Family history of pancreatic cancer
  • Genetic mutations (e.g., BRCA2 gene)
  • Chronic pancreatitis
  • Diabetes
  • Smoking
  • Obesity
  • Older age (risk increases after 50)
  • Diet high in red and processed meats
  • Heavy alcohol consumption
  • Exposure to certain chemicals (e.g., pesticides, dyes)

Treatment:

Treatment options include:

  • Surgery: Removing cancerous tissue from the pancreas, which may involve a Whipple procedure or distal pancreatectomy
  • Chemotherapy: Medications to kill cancer cells or shrink tumors before or after surgery
  • Radiation therapy: High-energy rays to target and destroy cancer cells
  • Targeted therapy: Drugs that specifically target cancer cell mechanisms
  • Immunotherapy: Boosting the body’s natural defenses to fight cancer
  • Palliative care: Managing symptoms and improving quality of life

For expert care and personalized treatment of pancreatic cancer, trust Dr. Pallabika Mandal’s expertise in surgical oncology. Contact us today to schedule a consultation and begin your journey toward recovery and wellness.